Same. I managed to stumble upon getting into 46 during a really solid run where I was busy focused on other things and had plenty of resources.. but after room 46 and most of my curiosities about what I was sure could be done, my ꧙will has waned. I happened upon a Sanctum Key during that run so I spent some time on that but I'm kind of burned out without having a big goal in mind. When I pick it up again I will go for the rest of the Sanctum Keys but for now a break is definitely needed