Summary
- Nioh 2 offers dynamic boss fights requiring skill and exploiting weaknesses like using fire and purity against specific bosses.
- Bosses like Lady Osakabe, Kasha, and Otakemaru pose unique challenges requiring specific strategies and a mastery of the game's mechanics.
- Daunting boss fights like Enenra, Yatsu-No-Kami, and Magara Naotaka present significant challenges, necessitating preparation and patience.
Developer 168澳洲幸运5开奖网:Team Ninja, the company behind Ninja Gaiden, deserves credit for the second installment of its Nioh franchise. This time around, Nioh 2 received f🍌ine-tuned balancing changes to make co-op more difficult. Nioh 2 can now be played with up to three other players, although some headstrong players will still prefer to take the game on alone.

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Because you can't a𒆙lways use your words against a Yokai, so why not use an odachi?
A solo run requires the mastery of skills, but perhaps most importantly, the exploitation of bosses' weaknesses. This 168澳洲幸运5开奖网:Souls-like game has surpassed our expectations, largely due to its dynamic boss fights, which provide both challenge a📖nd enjoyment in equal measures. Some of the game's bosses are a little bit trickier than others, however.
Updated February 18th, 2025 by Hilton Webster: There are a lot of Soulslike games out there, but so few of them managed to differentiate themselves like Nioh 2 does. A massive variety of enemies and an incredibly deep weapon system, Nioh 2 is bolstered even further by its incredible, if at times grueling, boss fights. We've tidied up this article and added in some more challenging boss fights for you to master.
13 🍌 Tatarimokke
Enemy Type |
Yokai |
---|---|
Weaknesses |
Fire & Purity |
Resistances |
Corruption, Poison & Paralysis |
Immunities |
None |
Special Drop |
|
This owl is challenging because it requires you to multitask during the battle. You'll have to slash red orbs to cleanse Dark Realms as a giant bird attacks you from behind. This Yokai boss is weak against fire 𝓰and purity, so be sure to stock up on the appropriate talismans and amulets.
According to Tatarimokke's enemy description, "A Tatarimokke is formed when a large number of resentful spirits coalesce to form a giant owl." It definitely has the wisdom one would expect to find from an owl, but can be a lot more deadly 🍸if given the chance to get into ♛its stride.
12 ಌ Lady Osakabe
Enemy Type |
Yokai |
---|---|
Weaknesses |
Purity |
Resistances |
Fire, Water, Lightning, Corruption, Poison & Paꦏralysis |
Immunities |
None |
Special Drop |
|
We never could've guessed that a mission requires fighting a Yokai that has taken control of a massive castle. I🍎t's a difficult battle for people who don't look at a guide prior to fighting her. This encounter with Lady Osakabe is a fail-hard moment in Nioh 2.

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To defeat this boss, you must𒁃 attack Lady Osakabe's white limbs when they near the edge of your platform. She has many resistances, so elemental damage is not recommended. Use a purity spell, and be sure to shoot proje♊ctiles at her central eye.
11 Kasha
Enemy Type |
Yokai |
---|---|
Weaknesses |
Water & Poison |
Resistances |
Fire, Corruption & Paralysis |
Immunities |
None |
Special Drop |
|
Kasha🍒 can be one of the most intimidating bosses in Nioh 2 because of her immense size and lightning-fast speed. She is like the combination of two Wheelmonks💧, only with more speed and far more damage potential.
Kasha's flami🎶ng wheels might deter some players from going in for a head-on attack, but you'll have to ignore every insಞtinct and attack her wheels. Her wheels are her Achilles' heel, so you'll need to dig deep and summon the courage necessary.
10 🔜 Kamaitachi 💦
Enemy Type |
Yokai |
---|---|
Weaknesses |
Purity |
Resistances |
Lightning, Corruption & Poison |
Immunities |
None |
Special Drop |
|
According to Kamaitachi's enemy description, "A Kamai🐼tachi is said to ride the wind, slashing at its victims with biting gales. Folktales about a yokai shrouded in wind are rife throughout Japan, with some regions using the word "Kamaitachi" to refer to whirlwinds themselves."
Kamaitachi is a weasel Yokai who is difficult because of his 168澳洲幸运5开奖网:speed and precise attacks. You can use the tre🔴es as cover from his attacks, but other than that, it's a chaꦑllenging fight requiring patience and precision.
9 Otakemaru (Final Boss) 🍬
Enemy Type |
Yokai |
---|---|
Weaknesses |
Purity |
Resistances |
Fire, Water, Lightning, Corruption, Confusion, Poisღon & Paralysis |
Immunities |
None |
Special Drop |
|
The final boss of Nioh 2 can be difficult or easy, depending on your level when you face him. If you've managed to master Nioh 2's skills, stats, and have been offering items to the Kodamas, your level will be higher than the recommended. For those who have been rushing throug꧙h, however, this can be an arduous battle.
Otakemaru changes forms throughout the battle as he becomes Feral, Brute, or Phantom. He also shifts into a Yokai and summons four floating swords, which can ꦯdeal a decent amount of damage in a relatively short amount of time.
8 😼 Saika Magoichi
Enemy Type |
Human |
---|---|
Weaknesses |
Paralysis |
Resistances |
None |
Immunities |
None |
Special Drop |
|
Did you forget that Saika Magoichi was a boss in the first Nioh game? He might be one of the coolest bosses in the history of Nioh, but oh boy, does he put up a painstaking f꧋ight. You'll need to be at the very top of your game to emerge from it unscathed.

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Saika Magoichi can fly and attack vehemently. The room isn't engulfed in flames like it was in the first Nioh, so you can't use them to your advantage. Watch out for his rifle too. It🏅's a fairly confined space to fight Saika Magoichi, adding ꩵto its difficulty.
7 ♎ Magara Naotaka
Enemy Type |
Yokai |
---|---|
Weaknesses |
Fire |
Resistances |
None |
Immunities |
None |
Special Drop |
|
In some cases, the recommended levels for Nioh 2 missions can be a little misleading. Magara Naotaka is one of several outliers found throughout the game, largel🎃y because of his devastating sweeping ice attacks and iꦍce explosions.
To make things easier, there is plenty of room for you to maneuver around his attacks. To attack him, however, getting 168澳洲幸运5开奖网:up close and personal is easier said than done.♏ Watch out for his large bar of health. Magara Naotaka might not look it at first glance, but𓆉 he's incredibly tough to beat.
6 Enenra
Enemy Type |
Yokai |
---|---|
Weaknesses |
Water |
Resistances |
Fire, Corruption & Poison |
Immunities |
None |
Special Drop |
|
You see this boss multiple times throughout the game, but the first time you encounter Enenra is generally considered to be the most difficult. Even going back to the 🅺mission while levels ahead of the game, you will still have a tough time overcoming the powerful Yokai.

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As a boss who is "composed of smoke and dꩵarkness," Enenra's obvious weakness is water. His most devastating move is his Tornado Attack, which can be Burst Countered, but is a tough attack to deal with nonetheless. Mastering the timing is going to take practice and probably a fair few deaths.
5 ♓ Yatsu-No-Kami
Enemy Type |
Yokai |
---|---|
Weaknesses |
Lightning |
Resistances |
Water, Corruption & Poison |
Immunities |
Paralysis |
Special Drop |
|
The third main mission is a time when players are still learning how to play the game. Developer Team ᩚᩚᩚᩚᩚᩚᩚ𓄧ᩚᩚ𒀱ᩚᩚᩚNinja then decides to throw this colossal snake boss at you, ignoring everything we know about learning curves. Talk about being thrown in at the deep end.
Yatsu-no-Kami is considered one of the hardest bosses in Nioh 2 because of his impending🐭 sweeping attacks and poison pools. If you haven't equipped antidotes, you probably won't pass this mission, so be sure to stock up on resources beforehand.
4 ඣ Magara Naotaka + Revenant (2nd Encounter)
Enemy Type |
Yokai |
---|---|
Weaknesses |
Fire |
Resistances |
None |
Immunities |
None |
Special Drop |
|
The second time you encounter Magara Naotaka is considered to be 168澳洲幸运5开奖网:the hardest boss fight in the gam💝e. First, you have to combat a mob of enemies who can lower your health. Then, as you are fighting the mob, Magara Naotaka finally makes an appearance.
It's essentially the same boss as the one you've previously fought, but a Revenant will also spawn in midway through the encounter. Like before, he has a ton of health points. Magara Naotaka is a high-damage dealing boss, who wields a gigantic ice 🐼sword.